Chaste Berry Extract

Chaste Berry Extract
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Chaste Berry Extract

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Vitex agnus-castus tree is a shrub that is native to the Mediterranean and Central Asia. The fruit and seed are used to make medicine. Vitex agnus-castus is used for conditions related to the menstrual cycle such as breast pain (mastalgia), premenstrual syndrome (PMS), and more severe PMS symptoms (premenstrual dysphoric disorder or PMDD). It is also used for many other conditions, but there is no good scientific evidence to support most of these uses.
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Technical Data Sheet

 

Product code

030847

Product

 Chaste Berry Extract

Specification

Aucubin0.6%+Agnuside0.5%

Part used

Fruits

Botanical source

Agnus castus

 

Items

Specification

Methods

Physical & chemical

Color

 

Brown

 

 

Organoleptic

Odor

Characteristic

Organoleptic

Appearance

Fine powder

Organoleptic

Analytical quality

Identification

 

Identical to R.S. sample

 

HPTLC

Sieve analysis

100% through 80 mesh

Eur.Ph.<2.9.12>

Loss on drying

≤5.0%

Eur.Ph.7.0 [2.8.17]

Total ash

≤10.0%

Eur.Ph.<2.4.16>

Bulk density

40~60g/100mL

Eur.Ph.<2.9.34>

Tap density

60~90g/100mL

Eur.Ph.<2.9.34>

Contaminants

Lead (Pb)

 

≤3.0mg/kg

 

Eur.Ph.<2.2.58>ICP-MS

Arsenic (As)

≤2.0mg/kg

Eur.Ph.<2.2.58>ICP-MS

Cadmium (Cd)

≤1.0mg/kg

Eur.Ph.<2.2.58>ICP-MS

Mercury (Hg)

≤0.1mg/kg

Eur.Ph.<2.2.58>ICP-MS

Solvents residue

Meet Eur. Ph. Requirements

Eur.Ph.<2.4.24>

Pesticides residue

Meet Eur. Ph. Requirements

Eur.Ph.<2.4.13>

Microbiological

Total plate count

 

≤10000cfu/g

 

Eur.Ph.<2.6.12>

Yeast & mold

≤1000cfu/g

Eur.Ph.<2.6.12>

E. Coli.

Negative

Eur.Ph.<2.6.13>

Salmonella

Negative

Eur.Ph.<2.6.13>

General Status

Non-Irradiation

 

≤700

 

EN13751:2002<PSL>

 

Net weight: 25kgs/Drum or Carton;

Gross weight: 27.5Kgs±0.5kg/Drum.

Packing size: Drum.I.D.35×H51cm; Carton 36cm×36cm×45cm

24 months under in a well-closed container and away from moisture, light, oxygen.

 

FLOW CHART OF Chaste berry extract

 

Chaste berry extract

 

Vitex agnus-castus tree is a shrub that is native to the Mediterranean and Central Asia. The fruit and seed are used to make medicine.

 

Vitex agnus-castus is used for conditions related to the menstrual cycle such as breast pain (mastalgia), premenstrual syndrome (PMS), and more severe PMS symptoms (premenstrual dysphoric disorder or PMDD). It is also used for many other conditions, but there is no good scientific evidence to support most of these uses.

 

How does it work

Vitex agnus-castus seems to affect many hormones that are involved in the female reproductive cycle.

 

Uses & Effectiveness

Possibly Effective for

Breast pain (mastalgia). Taking vitex agnus-castus daily seems to relieve pain in people who experience breast pain during the menstrual cycle.

Premenstrual syndrome (PMS). Some research shows that taking vitex agnus-castus decreases some symptoms of PMS, especially breast pain or tenderness, depressed mood or moodiness, anxiety, anger, and headache.

 

Possibly Ineffective for

Fractures. Taking vitex agnus-castus extract does not seem to improve the healing of broken bones.

 

Insufficient Evidence for

Inability to become pregnant within a year of trying to conceive (infertility). Early research shows that taking vitex agnus-castus does not improve the chance of becoming pregnant.

Insect repellent. Early research shows that applying vitex agnus-castus seed extract to the skin repels ticks and fleas for 6 hours, mosquitoes for 3 to 8 hours, and biting flies for 3 hours.

 

Side Effects

When taken by mouth: Vitex agnus-castus fruit extract is LIKELY SAFE for most people when taken appropriately for up to 3 months. Uncommon side effects include upset stomach, nausea, rash, headaches, acne, trouble sleeping, and weight gain. Some people notice a change in menstrual flow when they start taking vitex agnus-castus.

 

When applied to the skin:There isn't enough reliable information to know if vitex agnus-castus is safe or what the side effects might be.Special Precautions and Warnings

 

Pregnancy and breast-feeding: Using vitex agnus-castus during pregnancy or breast-feeding is POSSIBLY UNSAFE. The concern is that vitex agnus-castus can interfere with hormones. Don't use it if you are pregnant or breast-feeding.

 

Hormone-sensitive conditions such as endometriosis; uterine fibroids; or cancer of the breast, uterus, or ovaries: Vitex agnus-castus can affect hormones and might affect estrogen levels. Don't use vitex agnus-castus if you have a hormone-sensitive condition.

 

In vitro fertilization: Vitex agnus-castus can interfere with the effectiveness of in vitro fertilization. Don't use vitex agnus-castus if you are undergoing this procedure.

 

Parkinson disease. Vitex agnus-castus contains chemicals that affect the brain. These chemicals affect the brain similarly to some medications used for Parkinson disease. Therefore, vitex agnus-castus might affect therapy for Parkinson disease.

 

Schizophrenia or other psychotic disorders. Vitex agnus-castus seems to affect a chemical in the brain called dopamine. Some medications for mental disorders help to decrease dopamine. Therefore, taking vitex agnus-castus might affect therapy for certain mental disorders.

 

Interactions

Moderate Interaction

Be cautious with this combination

Birth control pills (Contraceptive drugs) interacts with VITEX AGNUS-CASTUS

Vitex agnus-castus seems to change hormone levels in the body. Birth control pills contain hormones. Taking vitex agnus-castus along with birth control pills might decrease the effectiveness of birth control pills and increase the chance of getting pregnant. If you take birth control pills along with vitex agnus-castus, use an additional form of birth control such as a condom.

Some birth control pills include ethinyl estradiol and levonorgestrel (Triphasil), ethinyl estradiol and norethindrone (Ortho-Novum 1/35, Ortho-Novum 7/7/7), and others.

 

Estrogens interacts with VITEX AGNUS-CASTUS

Vitex agnus-castus seems to change hormone levels in the body. Taking vitex agnus-castus along with estrogen pills might decrease the effects of estrogen pills.

Some estrogen pills include conjugated equine estrogens (Premarin), ethinyl estradiol, estradiol, and others.

 

Medications for mental conditions (Antipsychotic drugs) interacts with VITEX AGNUS-CASTUS

Vitex agnus-castus seems to affect a chemical in the brain called dopamine. Some medications for mental disorders help to decrease dopamine. Taking vitex agnus-castus along with these medications might decrease the effectiveness of some medications for mental conditions.

Some medications for mental conditions include chlorpromazine (Thorazine), clozapine (Clozaril), fluphenazine (Prolixin), haloperidol (Haldol), olanzapine (Zyprexa), perphenazine (Trilafon),), quetiapine (Seroquel), risperidone (Risperdal), thioridazine (Mellaril), thiothixene (Navane), and others.

 

Medications used for Parkinson disease (Dopamine agonists) interacts with VITEX AGNUS-CASTUS

Vitex agnus-castus contains chemicals that affect the brain. These chemicals affect the brain similarly to some medications used for Parkinson disease. Taking vitex agnus-castus with these medications might increase the effects and side effects of the medications used for Parkinson disease.

Some medications used for Parkinson disease include bromocriptine (Parlodel), levodopa (Dopar, component of Sinemet), pramipexole (Mirapex), ropinirole (Requip), and others.

 

Metoclopramide (Reglan) interacts with VITEX AGNUS-CASTUS

Vitex agnus-castus seems to affect a certain brain chemical called dopamine. Metoclopramide also affects dopamine. Taking vitex agnus-castus along with metoclopramide might decrease the

 

Dosing

BY MOUTH:

For breast pain (mastalgia): 3.2-4.8 mg of vitex agnus-castus dried fruit extract have been taken daily for 2 months. Also, 40 mg of vitex agnus-castus fruit extract has been taken daily for 3 months.

For premenstrual syndrome (PMS): Generally, 8-40 mg of vitex agnus-castus fruit extract has been taken daily for 2-3 menstrual cycles. A specific extract known as BNO 1095 (Agnucaston/Cyclodynon, Bionorica AG), which contains 4 mg of vitex agnus-castus extract has been taken daily for three menstrual cycles. Another specific extract known as Ze 440 (Prefemin, Max Zeller Sohne AG) which contains 20 mg of vitex agnus-castus fruit extract has been taken daily for three menstrual cycles. Another specific product (Femicur, Schaper & Brummer GmbH & Co. KG) containing 6.4-12 mg of vitex agnus-castus fruit extract has been taken daily in two divided doses for three menstrual cycles. Specific capsules (Agnolyt, Madaus AG) containing 3.5-4.2 mg of vitex agnus-castus dried fruit extract has been taken daily on days 16-35 over three menstrual cycles. Vitex agnus-castus fruit extract, 40 drops added to one glass of fruit juice once daily before breakfast starting 6 days prior to menstrual bleeding and lasting until menstrual bleeding occurs, has been used for six cycles.

 

From https://www.webmd.com/vitamins/ai/ingredientmono-968/vitex-agnus-castus

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Chaste Berry
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