Hops (Humulus lupulus) extract

Hops (Humulus lupulus) extract
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Hops (Humulus lupulus) extract

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Hops are the dried, flowering parts of the hop plant (Humulus lupulus), commonly used in brewing beer. They have limited evidence of health benefits. The term "hops" comes from the Anglo-Saxon term "hoppan", which means "to climb." Hops contain many chemicals, including bitter acids, which contribute to its bitter flavor. Some chemicals in hops seem to act similarly to the hormone estrogen and some seem to cause sleepiness. People commonly use hops for anxiety, sleep disorders, restlessness, symptoms of menopause, and many other conditions, but there is no good scientific evidence to support these uses.
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Technical Data Sheet/product specifications

 

Product

Hops extract

Product code

030546

Specification

4:1, TLC

Part used

Flower

Botanical source

Humulus lupulus L

Excipients

Maltodextrin5%

Extract solvent

Water

 

Items

Specification

Methods

Active ingredient

Total flavonoids 5%

HPLC

Physical & chemical

Color

Brown

 

Organoleptic

Odor

Characteristic

Organoleptic

 

 

 

Appearance

Fine powder

Organoleptic

Analytical quality

Identification

 

Identical to R.S. sample

 

HPTLC

Sieve analysis

90% through 80 mesh

Eur.Ph. <2.9.12>

Loss on drying

5.0%

Eur.Ph.7.0 [2.8.17]

Total ash

≤10.0%

Eur.Ph.<2.4.16>

Bulk density

40~60g/100mL

Eur.Ph.<2.9.34>

Tap density

60~90g/100mL

Eur.Ph.<2.9.34>

Contaminants

Lead (Pb)

 

≤3.0mg/kg

 

Eur.Ph.<2.2.58>ICP-MS

Arsenic (As)

≤2.0mg/kg

Eur.Ph.<2.2.58>ICP-MS

Cadmium (Cd)

≤1.0mg/kg

Eur.Ph.<2.2.58>ICP-MS

Mercury (Hg)

≤0.1mg/kg

Eur.Ph.<2.2.58>ICP-MS

Pesticides residue

Meet Eur.Ph. Requirements

Eur.Ph. <2.8.13>

 Aflatoxin (B1+B2+G1+G2)

 Meet Eur.Ph. Requirements

 EC No 1881/2006

 

PAHs

 ≤50ppb

 GC-MS

Microbiological

Total plate count

 

≤10000cfu/g

 

Eur.Ph. <2.6.12>

Yeast & mold

≤1000cfu/g

Eur.Ph. <2.6.12>

E. Coli.

Negative( Per 10grams)

Eur.Ph. <2.6.13>

Salmonella

Negative(Per 25grams)

Eur.Ph. <2.6.13>

General Status

Non-Irradiation

 

≤700

 

EN13751:2002<PSL>

Net weight: 25kgs/Drum or Carton

Gross weight: 27.5Kgs±0.5kg/Drum

Packing size: Drum.I.D.35×H51cm

24 months under in a well-closed container and away from moisture, light, oxygen.

Packed in paper-drums or carton with two plastic-bags inside.

 

FLOW CHART OF Hops extract

 

Hops extract  

 

Hops are the dried, flowering parts of the hop plant (Humulus lupulus), commonly used in brewing beer. They have limited evidence of health benefits.

 

The term "hops" comes from the Anglo-Saxon term "hoppan", which means "to climb." Hops contain many chemicals, including bitter acids, which contribute to its bitter flavor. Some chemicals in hops seem to act similarly to the hormone estrogen and some seem to cause sleepiness.

 

People commonly use hops for anxiety, sleep disorders, restlessness, symptoms of menopause, and many other conditions, but there is no good scientific evidence to support these uses.

 

Side Effects

When taken by mouth: Hops are commonly consumed in foods. Hops extracts and hops bitter acids are possibly safe when used short-term. Hops extracts have been used safely in doses of up to 300 mg daily for up to 3 months. Hops bitter acids have been used safely in doses of 35 mg daily for 3 months. Hops might cause dizziness and sleepiness in some people.

 

Special Precautions and Warnings

 

Pregnancy and breast-feeding: There isn't enough reliable information to know if hops are safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

 

Hormone sensitive cancers and conditions: Some chemicals in hops act like the hormone estrogen. People who have conditions that are sensitive to estrogen should use caution when taking hops. Some of these conditions include breast cancer and endometriosis.

 

Surgery: Hops might cause too much sleepiness when combined with anesthesia and other medications during and after surgical procedures. Stop taking hops at least 2 weeks before a scheduled surgery.

 

Interactions

 

Moderate Interaction

Be cautious with this combination

 

Sedative medications (CNS depressants) interacts with HOPS

Hops might cause sleepiness and slowed breathing. Some medications, called sedatives, can also cause sleepiness and slowed breathing. Taking hops with sedative medications might cause breathing problems and/or too much sleepiness.

 

Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates) interacts with HOPS

Some medications are changed and broken down by the liver. Hops might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

 

Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates) interacts with HOPS

Some medications are changed and broken down by the liver. Hops might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

 

Estrogens interacts with HOPS

Hops might have some of the same effects as estrogen. Taking hops along with estrogen might decrease the effects of estrogen.

 

Dosing

Hops are available in many different types of products, including beverages, tablets, capsules, creams, and gels. There isn't enough reliable information to know what an appropriate dose of hops might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.

 

from:https://www.webmd.com/vitamins/ai/ingredientmono-856/hops

 

 

 

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